Bioinformatics and evolution of non-model organisms

Mikhail S. Gelfand1,2

1Skolkovo Institute of Science and Technology, Moscow, Russia

2A.A.Kharkevich Institute for Information Transmission Problems, Moscow, Russia

mikhail.gelfand [at] gmail.com

Abstract

The textbooks are written based on Escherichia coli, Arabidopsis thaliana, Saccraromyces cerevisiae, Drosophila melanogaster, and mouse biology, with some contribution of less popular model species. However, interesting biology and evolution also happens elsewhere, and I’ll tell three such stories that have an evolutionary aspect in common: positive selection on mRNA editing in octopuses and their relatives, tetraplet codons in some ciliate infusoria and their seemingly neutral evolution, and (time permitting) recapitulation of the embryonic transcriptional program in insect pupae.

Keywords: comparative genomics, molecular evolution, coleoids, mRNA editing, Euplotes, frameshfting, genetic code, holometabolous insects, transcriptome, pupal development

Acknowledgement: This is joint work with Mikhail Moldovan, Sofya Gaydukova, Aleksandra Ozerova, Pavel Baranov partially supported by the RSF under grant 23-14-00136 and the RFBR under grant 20-54-14005.

Comments are closed.